I contacted a customer where we installed the new Tube Fx ...
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The effects loop is always used with a couple of Strymon (Flint/El Capistan) pedals for delay and reverb.
I really like being able to have the loop. I use the Trinity ODS with time based effects in the loop and in stereo with the two extension cabs. I have a switch that can send other effects in front and to the Trinity plus another amp as a dry rig (distortion, overdrive, etc.) it makes the sound really big without having to push the volume. The OSD is very articulate and the cleans are incredible. Even with overdrive it doesn’t get mushy. The wet/dry gives you the best of both worlds. Can keep the notes clear and articulate and sensitive to attack, while warming and fattening with the dry rig. I think having the active loop keeps one from having to rely only on special pedals and provides lots of flexibility with signal chain schemes: wet/dry, 4 cable etc.
As a side note the effects loop has really become transparent over time. It really is nice especially with the Strymon pedals.
I certainly don’t regret getting the loop and yes, I would recommend it.